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Azithromycin

Chemical Structure : Azithromycin

CAS No.: 83905-01-5

Azithromycin (CP 62993)

Catalog No.: PC-45307Not For Human Use, Lab Use Only.

A macrolide antibiotic used for the treatment of a number of bacterial infections.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A macrolide antibiotic used for the treatment of a number of bacterial infections; also attenuates myofibroblast differentiation and lung fibrosis development through proteasomal degradation of NOX4; also blocks autophagy by preventing lysosomal acidification.

Bacterial Infection

Approved

Physicochemical Properties

M.Wt 748.9845
Formula C38H72N2O12
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13

References

1. Tsubouchi K, et al. Autophagy. 2017 Jun 14:1-15.

2. Moriya S, et al. Int J Oncol. 2013 May;42(5):1541-50.

3. Renna M, et al. J Clin Invest. 2011 Sep;121(9):3554-63.

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