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B-973B

Chemical Structure : B-973B

CAS No.: 2244989-34-0

B-973B ((-)-B-973;B973B)

Catalog No.: PC-35867Not For Human Use, Lab Use Only.

B-973 (B973) is a potent, selective α7 nAChR ago-PAM, denonstrates analgesic effect with attenuating pain behavior and decreasing paw edema in vivo..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

B-973 (B973) is a potent, selective α7 nAChR ago-PAM, denonstrates analgesic effect with attenuating pain behavior and decreasing paw edema in vivo.

Physicochemical Properties

M.Wt 452.51
Formula C24H26F2N6O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-3-(3,4-difluorophenyl)-N-(1-(6-(4-(pyridin-2-yl)piperazin-1-yl)pyrazin-2-yl)ethyl)propanamide

References

1. Garai S, et al. ACS Med Chem Lett. 2018 Oct 11;9(11):1144-1148.

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