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BAY-218

Chemical Structure : BAY-218

CAS No.: 2162982-11-6

BAY-218 (BAY218)

Catalog No.: PC-23605Not For Human Use, Lab Use Only.

BAY-218 is a specific aryl hydrocarbon receptor (AHR) antagonist, inhibits AHR with IC50 of 39.9 nM in in U87 glioblastoma cells.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BAY-218 is a specific aryl hydrocarbon receptor (AHR) antagonist, inhibits AHR with IC50 of 39.9 nM in in U87 glioblastoma cells.

Physicochemical Properties

M.Wt 401.82
Formula C20H17ClFN3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-6-(4-Chlorophenyl)-2-(3-fluorophenyl)-N-(1-hydroxypropan-2-yl)-3-oxo-2,3-dihydropyridazine-4-carboxamide

References

1. Yang Z, et al. Toxicology. 2022 Apr 15;471:153175.

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