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Chemical Structure : BAY-6096
Catalog No.: PC-20307Not For Human Use, Lab Use Only.
BAY-6096 (BAY6096) is a potent, selective, and highly water-soluble adrenergic α2B antagonist with IC50 of 14 nM.
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BAY-6096 (BAY6096) is a potent, selective, and highly water-soluble adrenergic α2B antagonist with IC50 of 14 nM.
BAY-6096 displays >350-fold selectivity over α1A, α2A and α2C.
BAY-6096 shows high water-solublity (90 mg/mL), could be formulated in 0.9% NaCl solution showed no adsorption toward sterile filters and no instabilities upon heat steam sterilization.
BAY-6096 dose-dependently reduced blood pressure increases in rats induced by an α2B agonist.
| M.Wt | 426.91 | |
| Formula | C21H23ClN6O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Daniel Meibom, et al. J Med Chem. 2023 Mar 18. doi: 10.1021/acs.jmedchem.2c01690.
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