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Chemical Structure : BAY-678
CAS No.: 675103-36-3
Catalog No.: PC-60473Not For Human Use, Lab Use Only.
BAY-678 (BAY678) potent, selective, cell permeable human neutrophil elastase (HNE) inhibitor with IC50 of 20 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $118 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | $328 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
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BAY-678 (BAY678) potent, selective, cell permeable human neutrophil elastase (HNE) inhibitor with IC50 of 20 nM.
BAY-678 displays >2,000-fold selectivity over a panel of serine proteases (IC50>30 uM).
| M.Wt | 400.361 | |
| Formula | C20H15F3N4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
5-[(4R)-5-acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile |
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1. von Nussbaum F, et al. ChemMedChem. 2015 Jul;10(7):1163-73.
2. von Nussbaum F, et al. ChemMedChem. 2016 Jan 19;11(2):199-206.
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