BAY-678 |CAS:675103-36-3 Probechem Biochemicals

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Chemical Structure : BAY-678

CAS No.: 675103-36-3

BAY-678 (BAY678;BAY 678)

Catalog No.: PC-60473Not For Human Use, Lab Use Only.

BAY-678 (BAY678) potent, selective, cell permeable human neutrophil elastase (HNE) inhibitor with IC50 of 20 nM.

Packing	Price	Stock
10 mg	$118	In stock
25 mg	$198	In stock
50 mg	$328	In stock
100 mg		Get quote

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BAY-678 (BAY678) potent, selective, cell permeable human neutrophil elastase (HNE) inhibitor with IC50 of 20 nM.
BAY-678 displays >2,000-fold selectivity over a panel of serine proteases (IC50>30 uM).

Physicochemical Properties

M.Wt	400.361
Formula	C20H15F3N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-[(4R)-5-acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile

References

1. von Nussbaum F, et al. ChemMedChem. 2015 Jul;10(7):1163-73.

2. von Nussbaum F, et al. ChemMedChem. 2016 Jan 19;11(2):199-206.

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BAY-678 (BAY678;BAY 678)

Biological Activity

Physicochemical Properties

References

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