Chemical Structure : BAY1316957
CAS No.: 1613264-40-6
Catalog No.: PC-36057Not For Human Use, Lab Use Only.
BAY1316957 (BAY 1316957) is a highly potent, selective, orally available human prostaglandin E2 receptor subtype 4 (hEP4-R) antagonist with IC50 of 15.3 nM.
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BAY1316957 (BAY 1316957) is a highly potent, selective, orally available human prostaglandin E2 receptor subtype 4 (hEP4-R) antagonist with IC50 of 15.3 nM.
BAY1316957 significantly reduced pain related paw withdrawal behavior in the rat upon mechanical stimulation of the dmPGE2 treated hind paw.
| M.Wt | 441.531 | |
| Formula | C27H27N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: 100 mg/mL |
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| Chemical Name/SMILES |
2-(9-Ethyl-6-methyl-9H-carbazol-3-yl)-1-(2-methoxyethyl)-4-methyl-1H-benzimidazole-5-carboxylic acid |
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1. Bäurle S, et al. J Med Chem. 2019 Feb 1. doi: 10.1021/acs.jmedchem.8b01862.

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