Chemical Structure : BAY 2965501
CAS No.: 2732902-08-6
Catalog No.: PC-20666Not For Human Use, Lab Use Only.
BAY2965501 is a potent selective inhibitor of diacylglycerol kinases zeta (DGKζ), restores T-cell cellular DAG level and induces pERK activation in anergic T-cells via DGK inhibition to assist T-cell mediate tumor cell kill.
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BAY2965501 is a potent selective inhibitor of diacylglycerol kinases zeta (DGKζ), restores T-cell cellular DAG level and induces pERK activation in anergic T-cells via DGK inhibition to assist T-cell mediate tumor cell kill.
M.Wt | 414.46 | |
Formula | C20H19FN4O3S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
NC([C@@H](C)N(C1=CC=C(C=C1)F)C2=NC(N)=C(C(C3=CC=C(C=C3)OC)=O)S2)=O |
1. Nicole Schubert, et al. Cancer Res (2023) 83 (7_Supplement): 2116.
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