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BAY 2965501

Chemical Structure : BAY 2965501

CAS No.: 2732902-08-6

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BAY 2965501 (Veludacigib, BAY2965501)

Catalog No.: PC-20666Not For Human Use, Lab Use Only.

Veludacigib (BAY2965501) is a potent selective inhibitor of diacylglycerol kinases zeta (DGKζ), restores T-cell cellular DAG level and induces pERK activation in anergic T-cells via DGK inhibition to assist T-cell mediate tumor cell kill.

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50 mg $598 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Veludacigib (BAY2965501) is a potent selective inhibitor of diacylglycerol kinases zeta (DGKζ), restores T-cell cellular DAG level and induces pERK activation in anergic T-cells via DGK inhibition to assist T-cell mediate tumor cell kill.

Physicochemical Properties

M.Wt 414.46
Formula C20H19FN4O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(R)-2-((4-amino-5-(4-methoxybenzoyl)thiazol-2-yl)(4-fluorophenyl)amino)propanamide

References

1. Nicole Schubert, et al. Cancer Res (2023) 83 (7_Supplement): 2116.

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