Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-Guanylate Cyclase-BAY 60-2770
BAY 60-2770

Chemical Structure : BAY 60-2770

CAS No.: 1027642-43-8

BAY 60-2770 (BAY 602770, BAY60-2770)

Catalog No.: PC-63047Not For Human Use, Lab Use Only.

BAY 60-2770 is an NO-independent activator of sGC (soluble guanylyl cyclase) with EC50 of 5.4 nM.

Packing Price Stock Quantity
5 mg $128 In stock
10 mg $198 In stock
25 mg $348 In stock
50 mg $558 In stock
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BAY 60-2770 is an NO-independent activator of sGC (soluble guanylyl cyclase) with EC50 of 5.4 nM.
BAY 60-2770 demonstrates vasodilator activity in the pulmonary and systemic vascular beds that is enhanced by ODQ and NOS inhibition.

Physicochemical Properties

M.Wt 623.645
Formula C35H33F4NO5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-({(4-Carboxybutyl)[2-(5-fluoro-2-{[4'-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]amino}methyl)benzoic acid

References

1. Pankey EA, et al. Am J Physiol Heart Circ Physiol. 2011 Mar;300(3):H792-802.

2. Knorr A, et al. Arzneimittelforschung. 2008;58(2):71-80.

3. Jones AW, et al. J Pharmacol Exp Ther. 2010 Oct;335(1):85-91.

4. Mendes-Silverio CB, et al. PLoS One. 2012;7(11):e47223.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: