Chemical Structure : BAY85-8501
CAS No.:
1161921-82-9
BAY85-8501
(BAY 85-8501;BAY 858501)
Catalog No. : PC-60474Not For Human Use, Lab Use Only.
BAY 85-8501 (BAY85-8501) is a potent, selective human neutrophil elastase (HNE) inhibitor with IC50 of 65 pM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6047401
Biological Activity
BAY 85-8501 (BAY85-8501) is a potent, selective human neutrophil elastase (HNE) inhibitor with IC50 of 65 pM.
Physicochemical Properties
M.Wt
474.458
Formula
C22H17F3N4O3S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(S)-4-(4-cyano-2-(methylsulfonyl)phenyl)-3,6-dimethyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydropyrimidine-5-carbonitrile
References
1. von Nussbaum F, et al. ChemMedChem.
2. von Nussbaum F, et al. ChemMedChem.
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