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BB-78485

Chemical Structure : BB-78485

CAS No.: 207732-11-4

BB-78485 (BB78485)

Catalog No.: PC-26544Not For Human Use, Lab Use Only.

BB-78485 is a potent inhibitor of LpxC with IC50 of 160 nM in E. coli LpxC assays, showspredominantly gram-negative activities with MIC of 2 ug/mL for E.coli D21.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

BB-78485 is a potent inhibitor of LpxC with IC50 of 160 nM in E. coli LpxC assays, showspredominantly gram-negative activities with MIC of 2 ug/mL for E.coli D21.

Physicochemical Properties

M.Wt 420.48
Formula C23H20N2O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-N-Hydroxy-3-(naphthalen-2-yl)-2-(naphthalene-2-sulfonamido)propanamide

References

1. Clements JM,et al. Antimicrob Agents Chemother. 2002 Jun;46(6):1793-9.

2. Mochalkin I, et al. Protein Sci. 2008 Mar;17(3):450-7.

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