Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
EN | CN

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Tyrosine Kinase-RET Tyrosine Kinase (c-RET)-BBT594
BBT594

Chemical Structure : BBT594

CAS No.: 882405-89-2

Add to Favorites

BBT594 (NVP-BBT594, BBT-594)

Catalog No.: PC-45558Not For Human Use, Lab Use Only.

BBT594 (NVP-BBT594) is a potent RET inhibitor that can impairs GDNF-RET signaling and GDNF-dependent growth of MCF7-LTED cells.

Packing Price Stock Quantity
5 mg $98 In stock
10 mg $148 In stock
25 mg $258 In stock
50 mg $398 In stock
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BBT594 (NVP-BBT594) is a potent RET inhibitor that can impairs GDNF-RET signaling and GDNF-dependent growth of MCF7-LTED cells.
BBT594 significantly enhances the antiproliferative effects of letrozole (SF50=2.9 nM).

Physicochemical Properties

M.Wt 569.5781
Formula C28H30F3N7O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 33 mg/mL
Chemical Name/SMILES

1H-Indole-1-carboxamide, 5-[[6-(acetylamino)-4-pyrimidinyl]oxy]-2,3-dihydro-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-

References

1. Morandi A, et al. Cancer Res. 2013 Jun 15;73(12):3783-95.

2. Andreucci E, et al. Oncotarget. 2016 Dec 6;7(49):80543-80553.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: