BC11-38

Chemical Structure : BC11-38

CAS No.: 686770-80-9

Catalog No.: PC-23482Not For Human Use, Lab Use Only.

BC11-38 is a potent and selective PDE11 inhibitor with IC50 of 0.28 uM, without acitivity against PDE1-10.

Packing	Price	Stock
5 mg	$78	In stock
10 mg	$118	In stock
25 mg	$198	In stock
50 mg	$298	In stock
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Biological Activity

BC11-38 is a potent and selective PDE11 inhibitor with IC50 of 0.28 uM, without acitivity against PDE1-10.
BC11-38 significantly increases cAMP levels and cortisol production in H295R cells, both in the absence and presence of the adenylate cyclase activator forskolin.
BC11-38 effect is not observed in HeLa cells that have low PDE11 activity.

Physicochemical Properties

M.Wt	304.43
Formula	C15H16N2OS2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-Phenyl-2-(propylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one

References

1. Ceyhan O, et al. Chem Biol. 2012 Jan 27;19(1):155-63.

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BC11-38

Biological Activity

Physicochemical Properties

References

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