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BC8-15C

Chemical Structure : BC8-15C

CAS No.: 901263-25-0

BC8-15C

Catalog No.: PC-23481Not For Human Use, Lab Use Only.

BC8-15C is a potent, selective PDE11A inhibitor with IC50 of 0.08 uM in in vitro enzyme assays, also inhibits PDE4A with IC50 of 0.13 uM, shows little to no activity against PDE1, PDE2, PDE3, PDE5, PDE9, PDE10.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

BC8-15C is a potent, selective PDE11A inhibitor with IC50 of 0.08 uM in in vitro enzyme assays, also inhibits PDE4A with IC50 of 0.13 uM, shows little to no activity against PDE1, PDE2, PDE3, PDE5, PDE9, PDE10.

Physicochemical Properties

M.Wt 303.37
Formula C18H17N5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-ethyl-N-(m-tolyl)-[1,2,4]triazolo[4,3-c]quinazolin-5-amine

References

1. Demirbas D, et al. PLoS One. 2013 Aug 14;8(8):e71279.

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