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BCL6 inhibitor 7

Chemical Structure : BCL6 inhibitor 7

CAS No.: 2097518-46-0

BCL6 inhibitor 7

Catalog No.: PC-61017Not For Human Use, Lab Use Only.

A potent BCL6 protein-protein interaction inhibitor with Kd of 78 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A potent BCL6 protein-protein interaction inhibitor with Kd of 78 nM; exhibits an efficacy in cell-free and cellular PPI assays (ELISA IC50= 480 nM, M2H IC50= 8.6 uM).

Physicochemical Properties

M.Wt 366.809
Formula C18H15ClN6O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-((5-Chloro-2-((pyridin-3-ylmethyl)amino)pyrimidin-4-yl)-amino)-1,3-dihydro-2H-indol-2-one

References

1. Kamada Y, et al. J Med Chem. 2017 May 25;60(10):4358-4368.

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