Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-GPCR-Sigma Receptor-BD-1063 dhydrochloride
BD-1063 dhydrochloride

Chemical Structure : BD-1063 dhydrochloride

CAS No.: 206996-13-6

BD-1063 dhydrochloride (BD1063 dhydrochloride)

Catalog No.: PC-45420Not For Human Use, Lab Use Only.

BD-1063 dhydrochloride (BD1063) is a potent, selective sigma-1 receptor antagonist with binding Ki of 9 nM.

Packing Price Stock Quantity
10 mg $108 In stock
25 mg $188 In stock
50 mg $298 In stock
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BD-1063 dhydrochloride (BD1063) is a potent, selective sigma-1 receptor antagonist with binding Ki of 9 nM.
BD-1063 displays >49-fold selectivity over the sigma-2 receptor.
BD-1063 significantly reverses the neuroprotective effect of DHEA-S against NMDA-induced neurotoxicity in rat hippocampal neurons.

Physicochemical Properties

M.Wt 346.1233
Formula C13H20Cl4N2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

100 mM in H2O

Chemical Name/SMILES

Piperazine, 1-[2-(3,4-dichlorophenyl)ethyl]-4-methyl-, hydrochloride (1:2)

References

1. Matsumoto RR, et al. Eur J Pharmacol. 2001 May 11;419(2-3):163-74.

2. Matsumoto RR, et al. Eur J Pharmacol. 1995 Jul 14;280(3):301-10.

3. Wu Z, et al. J Biol Chem. 2008 Oct 17;283(42):28198-215.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: