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BDM49234

Chemical Structure : BDM49234

CAS No.: 618405-72-4

BDM49234 (BDM 49234)

Catalog No.: PC-20242Not For Human Use, Lab Use Only.

BDM49234 is a selective small molecule inhibitor of anti-apoptotic protein BCL2A1/Bfl-1 with IC50 of 6.3 uM (inhibition FITC–Bim BH3 binding to Bfl-1).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    BDM49234 is a selective small molecule inhibitor of anti-apoptotic protein BCL2A1/Bfl-1 with IC50 of 6.3 uM (inhibition FITC–Bim BH3 binding to Bfl-1).

    Physicochemical Properties

    M.Wt 359.49
    Formula C22H21N3S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-((2-methyl-1H-indol-3-yl)(4-(methylthio)phenyl)methyl)pyridin-2-amine

    References

    1. Anne-Laure Mathieu, et al. J Biomol Screen. 2014 Aug;19(7):1035-46.

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