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Chemical Structure : BDM71339
Catalog No.: PC-49180Not For Human Use, Lab Use Only.
BDM71339 is the first small molecule inhibitor of mycobacterial transcriptional regulator EthR, boosts ten times the activity of ethionamide in TB-infected macrophages at low nanomolar concentrations (EC50=72 nM) in vitro.
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BDM71339 is the first small molecule inhibitor of mycobacterial transcriptional regulator EthR, boosts ten times the activity of ethionamide in TB-infected macrophages at low nanomolar concentrations (EC50=72 nM) in vitro.
BDM71339 is active in vivo in acute model of tuberculosis infection.
| M.Wt | 325.291 | |
| Formula | C15H14F3N3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Baptiste Villemagne, et al. ACS Infect Dis. 2020 Mar 13;6(3):366-378.
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