BDM_92499 | IRAP inhibitor | Probechem Biochemicals

Chemical Structure : BDM_92499

BDM_92499 (BDM-92499, BDM92499)

Catalog No.: PC-23920Not For Human Use, Lab Use Only.

BDM_92499 is a potent, selective inhibitor of insulin-regulated aminopeptidase IRAP with IC50 of 3.4 nM has >150-fold selecive\ity over ERAP1 and ARAP2.

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Biological Activity

BDM_92499 is a potent, selective inhibitor of insulin-regulated aminopeptidase IRAP with IC50 of 3.4 nM has >150-fold selecive\ity over ERAP1 and ARAP2.

Physicochemical Properties

M.Wt	466.54
Formula	C25H30N4O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[(1S)-2-Amino-1-[(5-benzyloxy-1H-indol-3-yl)methyl]-2-oxo-ethyl]-2-(hydroxycarbamoyl)-4-methyl-pentanamide

References

1. He B, et al. J Med Chem. 2025 Feb 7. doi: 10.1021/acs.jmedchem.4c01744.

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BDM_92499 (BDM-92499, BDM92499)

Biological Activity

Physicochemical Properties

References

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