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BE21417

Chemical Structure : BE21417

CAS No.:

BE21417 (BE-21417)

Catalog No.: PC-27244Not For Human Use, Lab Use Only.

BE21417 is a potent, selective dual inhibitor of carbonic anhydrases hCA IX and XII, exhibits a nearly 6-fold preference for hCA XII over hCA II.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

BE21417 is a potent, selective dual inhibitor of carbonic anhydrases hCA IX and XII, exhibits a nearly 6-fold preference for hCA XII over hCA II.

Physicochemical Properties

M.Wt 517.78
Formula C21H14BrClN4O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-4-(6-bromo-3-((2-chlorobenzylidene)amino)-4-oxo-3,4-dihydroquinazolin-2-yl)benzenesulfonamide

References

1. Hazem Essam Okda, et al. J Med Chem. 2026 Jul 9;69(13):16036-16060.

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