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Chemical Structure : BFA1
Catalog No.: PC-21549Not For Human Use, Lab Use Only.
BFA1 is a specific small-molecule activator of Burkholderia FixLJ signaling pathway, inhibit the virulence of multiple pathogenic Burkholderia species.
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BFA1 is a specific small-molecule activator of Burkholderia FixLJ signaling pathway, inhibit the virulence of multiple pathogenic Burkholderia species.
BFA1 inhibit B. dolosa virulence in THP-1-derived macrophages in a fixLJ-specific manner.
BFA1 is predicted to bind to FixL at the ATP/ADP-binding pocket of the histidine kinase domain.
| M.Wt | 404.47 | |
| Formula | C24H24N2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kathryn E Mansour, et al. bioRxiv. 2023 Dec 2:2023.12.02.569726.
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