Chemical Structure : BI-167107
CAS No.: 1202235-68-4
Catalog No.: PC-35028Not For Human Use, Lab Use Only.
BI-167107 (BI 167107) is a highly potent agonist of the β2 adrenergic receptor (β2AR) and β1AR (IC50=3.2 nM) and shows some activity as α1A antagonist (IC50 = 32 nM).
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BI-167107 (BI 167107) is a highly potent agonist of the β2 adrenergic receptor (β2AR) and β1AR (IC50=3.2 nM) and shows some activity as α1A antagonist (IC50 = 32 nM).
| M.Wt | 370.449 | |
| Formula | C21H26N2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
5-hydroxy-8-(1-hydroxy-2-((2-methyl-1-(o-tolyl)propan-2-yl)amino)ethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one |
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1. Weiss DR, et al. ACS Chem Biol. 2013 May 17;8(5):1018-26.
2. Ring AM, et al. Nature. 2013 Oct 24;502(7472):575-579.
3. Manglik A, et al. Cell. 2015 May 21;161(5):1101-1111.
4. Kahsai AW, et al. Nat Chem Biol. 2016 Sep;12(9):709-16.

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