BI-4732 | EGFR inhibitor | Probechem Biochemicals

Chemical Structure : BI-4732

Catalog No.: PC-21761Not For Human Use, Lab Use Only.

BI-4732 is a potent, highly BBB penetrant, fourth-generation EGFR inhibitor against EGFR activating mutations, including C797S.

Packing	Price	Stock	Quantity
50 mg		Get quote
100 mg		Get quote
200 mg		Get quote
1 g		Get quote

Get Quotation Now

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BI-4732 is a potent, highly BBB penetrant, fourth-generation EGFR inhibitor against EGFR activating mutations, including C797S.

M.Wt	592.69
Formula	C32H36N10O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(1R,4R)-5-[2-[(8aR)-Hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl]-6-[6-(4-methoxy-3-pyridinyl)-4-methyl-1H-pyrazolo[4,3-c]pyridin-1-yl]-1-methyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-oxa-5-azabicyclo[2.2.1]heptane

1. Eun Ji Lee, et al. Clin Cancer Res. 2024 Feb 8. doi: 10.1158/1078-0432.CCR-23-2951.