BI-4924 | PHGDH inhibitor | Probechem Biochemicals

Chemical Structure : BI-4924

CAS No.: 2244452-09-1

BI-4924 (BI 4924)

Catalog No.: PC-72878Not For Human Use, Lab Use Only.

BI-4924 (BI 4924) is a potent, selective NADH/NAD+-competitive PHGDH inhibitor with IC50 of 2 nM.

Packing	Price	Stock
2 mg	$258	In stock
5 mg	$458	In stock
10 mg	$758	In stock
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Biological Activity

BI-4924 (BI 4924) is a potent, selective NADH/NAD+-competitive PHGDH inhibitor with IC50 of 2 nM.
BI-4924 displays high selectivity against the majority of other dehydrogenase targets.

Physicochemical Properties

M.Wt	499.359
Formula	C21H20Cl2N2O6S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-{4-[(1S)-1-[(4,5-Dichloro-1,6-dimethyl-1H-indol-2-yl)formamido]-2-hydroxyethyl]benzenesulfonyl}acetic acid

References

1. Harald Weinstabl, et al. J Med Chem. 2019 Sep 12;62(17):7976-7997.

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BI-4924 (BI 4924)

Biological Activity

Physicochemical Properties

References

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