Chemical Structure : BI-D1870
CAS No.:
501437-28-1
BI-D1870
(BI-D 1870)
Catalog No. : PC-42627Not For Human Use, Lab Use Only.
BI-D1870 is a potent, specific ATP-competitive inhibitor of RSK isoforms with IC50 of 10-30 nM for RSK1/2/3/4.
Packing Price Stock Quantity 5 mg $98 In stock 0 1 2 3 4 5 10 mg $148 In stock 0 1 2 3 4 5 25 mg $258 In stock 0 1 2 3 4 5 50 mg $398 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4262701
Biological Activity
BI-D1870 is a potent, specific ATP-competitive inhibitor of RSK isoforms with IC50 of 10-30 nM for RSK1/2/3/4.
Physicochemical Properties
M.Wt
391.415
Formula
C19H23F2N5O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
6(5H)-Pteridinone, 2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7,8-dihydro-5,7-dimethyl-8-(3-methylbutyl)-
References
1. Sapkota GP, et al. Biochem J.
2. Neise D, et al. Cell Death Dis.
3. Fonseca BD, et al. J Biol Chem.
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