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BI 187004

Chemical Structure : BI 187004

CAS No.: 1303515-32-3

BI 187004 (BI187004;VTP-34072)

Catalog No.: PC-63215Not For Human Use, Lab Use Only.

BI 187004 (VTP-34072) is a novel potent, selective 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor intended to treat type 2 diabetes mellitus (T2D)..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BI 187004 (VTP-34072) is a novel potent, selective 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor intended to treat type 2 diabetes mellitus (T2D).

Physicochemical Properties

M.Wt 342.402
Formula C21H18N4O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(4aR,9aS)-1-(1H-benzo[d]imidazole-5-carbonyl)-2,3,4,4a,9,9a-hexahydro1H-indeno[2,1-b]pyridine-6-carbonitrile

References

1. Maw HH, et al. Drug Metab Dispos. 2018 Mar 7. pii: dmd.117.079764.

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