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BI 703704

Chemical Structure : BI 703704

CAS No.: 1423067-48-4

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BI 703704 (BI-703704;BI703704)

Catalog No.: PC-60643Not For Human Use, Lab Use Only.

BI 703704 is a potent soluble guanylate cyclase (sGC) activator, reduces progression of renal damage in the ZSF1 rat, shows the potential as an effective therapy for diabetic nephropathy.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    BI 703704 is a potent soluble guanylate cyclase (sGC) activator, reduces progression of renal damage in the ZSF1 rat, shows the potential as an effective therapy for diabetic nephropathy.

    Physicochemical Properties

    M.Wt 559.725
    Formula C32H37N3O4S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (1R,5S,8s)-3-(4-(5-methyl-2-((2-methyl-4-(piperidine-1-carbonyl)benzyl)oxy)phenyl)thiazol-2-yl)-3-azabicyclo[3.2.1]octane-8-carboxylic acid

    References

    1. Boustany-Kari CM, et al. J Pharmacol Exp Ther. 2016 Mar;356(3):712-9.

    2. Stasch JP, et al. Curr Opin Pharmacol. 2015 Apr;21:95-104.

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