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Chemical Structure : BIIL260
Catalog No.: PC-63301Not For Human Use, Lab Use Only.
BIIL260 is the active metabolite of BIIL284, shows high affinity to LTB4 receptor on isolated human neutrophil cell membranes with Ki of 1.7 nM.
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BIIL260 is the active metabolite of BIIL284, shows high affinity to LTB4 receptor on isolated human neutrophil cell membranes with Ki of 1.7 nM.
BIIL260 potently inhibits LTB(4)-induced intracellular Ca(2+) release in human neutrophils with IC50 of 0.82 nM, interacts with the LTB(4) receptor in a saturable, reversible, and competitive manner.
| M.Wt | 466.581 | |
| Formula | C30H30N2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Hori T, et al. Nat Chem Biol. 2018 Mar;14(3):262-269.
2. Birke FW, et al. J Pharmacol Exp Ther. 2001 Apr;297(1):458-66.
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