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BIM1

Chemical Structure : BIM1

CAS No.: 2247911-40-4

BIM1

Catalog No.: PC-27985Not For Human Use, Lab Use Only.

BIM1 is a specific small molecule inhibitor of chloride channel CLC-Ka (CLCNKA) with IC50 of 8.5 uM, >20-fold selectivity for CLC-Ka over CLC-Kb.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

BIM1 is a specific small molecule inhibitor of chloride channel CLC-Ka (CLCNKA) with IC50 of 8.5 uM, >20-fold selectivity for CLC-Ka over CLC-Kb.

Physicochemical Properties

M.Wt 381.27
Formula C13H7Cl2KN2O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

potassium 6-chloro-1-(2-chlorophenyl)-1H-benzo[d]imidazole-2-sulfonate

References

1. Koster AK, et al. Proc Natl Acad Sci U S A. 2018 May 22;115(21):E4900-E4909.

2. Chien CT, et al. Proc Natl Acad Sci U S A. 2026 Sep 8;123(36):e2605886123.

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