BL-140 | p110β inhibitor | Probechem Biochemicals

Chemical Structure : BL-140

BL-140 (BL 140, BL140)

Catalog No.: PC-60391Not For Human Use, Lab Use Only.

BL-140 is a potent, specific p110β inhibitor with IC50 of 5.74 nM.

Packing	Price	Stock	Quantity
50 mg		Get quote
100 mg		Get quote
200 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

BL-140 is a potent, specific p110β inhibitor with IC50 of 5.74 nM.
BL-140 dispalys 150-fold and 745-fold selectivity over p110α or p110δ.
BL-140 blocks G1 phase cell cycle entry by reducing cyclin D1 but increasing p27kip1 protein levels, overcomes MDV3100-resistance in castration-resistant prostate cancer cells.

Physicochemical Properties

M.Wt	371.459
Formula	C18H21N5O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	7-methyl-2-morpholino-9-(1-(thiazol-2-ylamino)ethyl)-4H-pyrido[1,2-a]pyrimidin-4-one

References

1. He C, et al. Prostate. 2017 Aug;77(11):1187-1198.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

BL-140 (BL 140, BL140)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.