Chemical Structure : BLI-489
Catalog No.: PC-38335Not For Human Use, Lab Use Only.
BLI-489 is a bicyclic penem inhibitor that inhibits class A, C, and D beta-lactamases with synergistic effects with piperacillin.
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BLI-489 is a bicyclic penem inhibitor that inhibits class A, C, and D beta-lactamases with synergistic effects with piperacillin.
The combination of piperacillin-BLI-489 demonstrated improved activity compared to that of piperacillin-tazobactam against the problematic extended-spectrum beta-lactamase- and AmpC-expressing strains.
M.Wt | 305.31 | |
Formula | C13H11N3O4S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Peter J Petersen, et al. Antimicrob Agents Chemother. 2009 Feb;53(2):370-84.
2. Petersen PJ, et al. Antimicrob Agents Chemother. 2009 Apr;53(4):1698-700.
3. Wang YC, et al. J Antimicrob Chemother. 2021 Jan 19;76(2):451-459.
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