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Chemical Structure : BLT-1
Catalog No.: PC-62034Not For Human Use, Lab Use Only.
BLT-1 is an irreversible Scavenger receptor class B member I (SR-BI) inhibitor that blocks SR-BI-mediated selective lipid uptake and bidirectional cholesterol flux with an IC50 of 50 nM.
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BLT-1 is an irreversible Scavenger receptor class B member I (SR-BI) inhibitor that blocks SR-BI-mediated selective lipid uptake and bidirectional cholesterol flux with an IC50 of 50 nM; significantly inhibits baicalin-induced cholesterol efflux in THP-1 macrophages.
| M.Wt | 241.397 | |
| Formula | C12H23N3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Yu M, et al. Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12243-8.
2. Nieland TJ, et al. J Lipid Res. 2007 Aug;48(8):1832-45. Epub 2007 May 28.
3. Yu R, et al. Exp Ther Med. 2016 Dec;12(6):4113-4120.
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