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BLU-667 trans form

Chemical Structure : BLU-667 trans form

CAS No.: 2097132-93-7

BLU-667 trans form

Catalog No.: PC-35951Not For Human Use, Lab Use Only.

BLU-667 trans form is the trans form of BLU-667, which is a highly potent, selective, next generation RET inhibitor..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

BLU-667 trans form is the trans form of BLU-667, which is a highly potent, selective, next generation RET inhibitor.

Physicochemical Properties

M.Wt 533.612
Formula C27H32FN9O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(1r,4S)-N-((S)-1-(6-(4-fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethyl)-1-methoxy-4-(4-methyl-6-((5-methyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)cyclohexane-1-carboxamide

References

1. Subbiah V, et al. Cancer Discov. 2018 Apr 15. pii: CD-18-0338.

2. Piotrowska Z, et al. Cancer Discov. 2018 Dec;8(12):1529-1539.

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