Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Tyrosine Kinase-c-Kit-BLU-808
BLU-808

Chemical Structure : BLU-808

CAS No.: 3041025-10-6

Add to Favorites

BLU-808 (BLU808, BLU 808)

Catalog No.: PC-21781Not For Human Use, Lab Use Only.

BLU-808 (BLU808) is a potent and selective wt c-KIT inhibitor, inhibits the autophosphorylation of wild-type c-Kit with IC50 of 0.3 nM, inhibits Exon 11 KIT with an IC50 of 0.9 nM.

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    BLU-808 (BLU808) is a potent and selective wt c-KIT inhibitor, inhibits the autophosphorylation of wild-type c-Kit with IC50 of 0.3 nM, inhibits Exon 11 KIT with an IC50 of 0.9 nM.
    BLU-808 potently inhibits c-KIT-dependent phosphorylation and proliferation with IC50 values in the sub-nanomolar and nanomolar range, respectively.

    Physicochemical Properties

    M.Wt 529.58
    Formula C27H28FN9O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(5-(2-Cyclopropyl-2H-tetrazol-5-yl)-4-fluoro-2-methylphenyl)-5-(1-(2-hydroxy-2-methylpropyl)-3-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carboxamide

    References

    1. Patent WO2025255219A1. WIPO (PCT). 2025-06-04.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: