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Chemical Structure : BMD4722
Catalog No.: PC-20574Not For Human Use, Lab Use Only.
BMD4722 is a highly potent, small-molecule inhibitor of Dvl-CXXC5 interaction with IC50 of 2.59 uM, directly binds to the Dvl PDZ domain (Kd=22.3 uM).
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BMD4722 is a highly potent, small-molecule inhibitor of Dvl-CXXC5 interaction with IC50 of 2.59 uM, directly binds to the Dvl PDZ domain (Kd=22.3 uM).
BMD4722 effectively disrupted the interaction between Dvl PDZ domain and the DBM peptide in competitive Dvl-CXXC5 binding assays.
| M.Wt | 594.50 | |
| Formula | C31H32BrNO6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Songling Ma, et al. J Comput Aided Mol Des. 2018 May;32(5):643-655.
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