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Chemical Structure : BMS-192364
CAS No.: 202822-21-7
Catalog No.: PC-23050Not For Human Use, Lab Use Only.
BMS-192364 is a small molecule inhibitor of muscarinic G-protein coupled receptor (GPCR) signaling involving G-αq (G-protein alpha subunit), likely acts at the intersection of RGS and G-αq proteins, resulting in the downregulation of GPCR signaling, reduced calcium fluxes, and reduced muscle contraction.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $288 | In stock | |
| 10 mg | $458 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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BMS-192364 is a small molecule inhibitor of muscarinic G-protein coupled receptor (GPCR) signaling involving G-αq (G-protein alpha subunit) and an RGS protein agonist, likely acts at the intersection of RGS and G-αq proteins, resulting in the downregulation of GPCR signaling, reduced calcium fluxes, and reduced muscle contraction.
| M.Wt | 355.70 | |
| Formula | C15H9ClF3N3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-(5-Chloro-2-hydroxyphenyl)-1,2-dihydro-5-[4-(trifluoromethyl)phenyl]-3H-1,2,4-triazol-3-one |
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1. Kevin Fitzgerald, et al. PLoS Genet. 2006 Apr;2(4):e57.
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