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BMS-202

Chemical Structure : BMS-202

CAS No.: 1675203-84-5

BMS-202 (PCC0208025, BMS202, BMS 202, 5J89LIG)

Catalog No.: PC-45701Not For Human Use, Lab Use Only.

BMS-202 (PCC0208025) is a small molecule inhibitor of the PD-1/PD-L1 interaction with IC50 of 18 nM in a homogenous time-resolved fluorescence binding assay.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BMS-202 (PCC0208025) is a small molecule inhibitor of the PD-1/PD-L1 interaction with IC50 of 18 nM in a homogenous time-resolved fluorescence binding assay.

Physicochemical Properties

M.Wt 419.5161
Formula C25H29N3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 30 mg/mL

Chemical Name/SMILES

Acetamide, N-[2-[[[2-methoxy-6-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]-3-pyridinyl]methyl]amino]ethyl]-

References

1. Louis S. Chupak, et al. Compounds useful as immunomodulators. WO 2015034820 A1.

2. Guzik K, et al. J Med Chem. 2017 Jul 13;60(13):5857-5867.

3. Zak KM, et al. Structure. 2017 Aug 1;25(8):1163-1174.

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