Catalog No.: PC-60688Not For Human Use, Lab Use Only.
Flindokalner (BMS-204352) is a potent and effective calcium-sensitive opener of maxi-K potassium channels (maxi-K) with EC50 of 392 nM at -48.4 mV in HEK293 isolated outside-out membrane patches.
Flindokalner (BMS-204352) is a potent and effective calcium-sensitive opener of maxi-K potassium channels (maxi-K) with EC50 of 392 nM at -48.4 mV in HEK293 isolated outside-out membrane patches.
Flindokalner (BMS-204352) is a potent and effective opener of two important subtypes of neuronal potassium channels, K(Ca) channels and KCNQ channels, strongly activates the voltage-gated K+ channel KCNQ5 with EC50 of 2.4 uM.
Flindokalner (BMS-204352)shows significant levels of cortical neuroprotection in rat models of permanent large-vessel stroke.
