Chemical Structure : BMS-299897
CAS No.:
290315-45-6
BMS-299897
(BMS 299897, BMS299897)
Catalog No. : PC-45889Not For Human Use, Lab Use Only.
BMS-299897 is a potent γ-secretase inhibitor that preferentially inhibits cleavage of the APP CTF cleavage with IC50 of 7.1 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4588901
Biological Activity
BMS-299897 is a potent γ-secretase inhibitor that preferentially inhibits cleavage of the APP CTF cleavage with IC50 of 7.1 nM.
Physicochemical Properties
M.Wt
511.941
Formula
C24H21ClF3NO4S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 30 mg/mL
Chemical Name/SMILES
Benzenebutanoic acid, 2-[(1R)-1-[[(4-chlorophenyl)sulfonyl](2,5-difluorophenyl)amino]ethyl]-5-fluoro-
References
1. Barten DM, et al. J Pharmacol Exp Ther.
2. Meunier J, et al. Eur J Pharmacol.
3. Goldstein ME, et al. J Pharmacol Exp Ther.
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