Chemical Structure : BMS-599626 hydrochloride
CAS No.:
873837-23-1
BMS-599626 hydrochloride
(AC480, BMS599626, AC-480)
Catalog No. : PC-42825Not For Human Use, Lab Use Only.
BMS-599626 (AC-480) is a potent, selective inhibitor of EGFR and HER2 with IC50 of 20 nM and 30 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4282501
Biological Activity
BMS-599626 (AC-480) hydrochloride is a potent, selective inhibitor of EGFR and HER2 with IC50 of 20 nM and 30 nM.
Physicochemical Properties
M.Wt
567.0144
Formula
C27H28ClFN8O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Carbamic acid, [4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]-, (3S)-3-morpholinylmethyl ester, monohydrochloride (9CI)
References
1. Gavai AV, et al. J Med Chem.
2. Wong TW, et al. Clin Cancer Res
3. Haluska P, et al. Mol Cancer Ther
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