Chemical Structure : BMS-690514
CAS No.:
859853-30-8
BMS-690514
(BMS690514;BMS 690514)
Catalog No. : PC-42532Not For Human Use, Lab Use Only.
BMS-690514 is a potent pan EGFR/VEGFR inhibitor with IC50 of 5/20/60/50 nM for EGFR/HER2/ERBB4/VEGFR2 respectively.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4253201
Biological Activity
BMS-690514 is a potent pan EGFR/VEGFR inhibitor with IC50 of 5/20/60/50 nM for EGFR/HER2/ERBB4/VEGFR2 respectively.
Physicochemical Properties
M.Wt
368.4329
Formula
C19H24N6O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
3-Piperidinol, 4-amino-1-[[4-[(3-methoxyphenyl)amino]pyrrolo[2,1-f][1,2,4]triazin-5-yl]methyl]-, (3R,4R)-
References
1. de La Motte Rouge T, et al. Cancer Res. 2007 Jul 1;67(13):6253-62.
2. Wong TW, et al. Clin Cancer Res. 2011 Jun 15;17(12):4031-41.
3. Loriot Y, et al. Br J Cancer. 2010 Jul 27;103(3):347-53.
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