BMS-698861 | Probechem Biochemicals

Chemical Structure : BMS-698861

BMS-698861 (BMS698861)

Catalog No.: PC-62912Not For Human Use, Lab Use Only.

BMS-698861 is a potent γ-secretase modulator (GSM) that decreases levels of all the peptides, Aβ1-40, Aβ1-42, Aβ1-38, Aβ1-37 and Aβ1-x, results in APP-CTFβ and APP-CTFα accumulation in brain.

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Biological Activity

BMS-698861 is a potent γ-secretase modulator (GSM) that decreases levels of all the peptides, Aβ1-40, Aβ1-42, Aβ1-38, Aβ1-37 and Aβ1-x, results in APP-CTFβ and APP-CTFα accumulation in brain.

Physicochemical Properties

M.Wt	478.923
Formula	C21H20ClFN4O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-2-((4-chloro-N-(2-fluoro-4-(1,2,4-oxadiazol-3-yl)benzyl)phenyl)sulfonamido)-3-cyclopropylpropanamide

References

1. Toyn JH, et al. Int J Alzheimers Dis. 2014;2014:431858.

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BMS-698861 (BMS698861)

Biological Activity

Physicochemical Properties

References

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