BMS-707035 |CAS:729607-74-3 Probechem Biochemicals

Chemical Structure : BMS-707035

CAS No.: 729607-74-3

Catalog No.: PC-43448Not For Human Use, Lab Use Only.

BMS-707035 is a potent, specific, and reversible HIV-I integrase (IN) inhibitor that blocks HIV IN strand transfer activity with IC50 of 15 nM..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BMS-707035 is a potent, specific, and reversible HIV-I integrase (IN) inhibitor that blocks HIV IN strand transfer activity with IC50 of 15 nM.

HIV Infection

Phase 2 Discontinued

M.Wt	410.42
Formula	C17H19FN4O5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-Pyrimidinecarboxamide, N-[(4-fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-6-oxo-2-(tetrahydro-1,1-dioxido-2H-1,2-thiazin-2-yl)-

1. Dicker IB, et al. J Biol Chem. 2007 Oct 26;282(43):31186-96.

2. Langley DR, et al. Biochemistry. 2008 Dec 23;47(51):13481-8.

3. Al-Mawsawi LQ, et al. Expert Opin Emerg Drugs. 2008 Jun;13(2):213-25.