BMS-794833 |CAS:1174046-72-0 Probechem Biochemicals

Chemical Structure : BMS-794833

CAS No.: 1174046-72-0

BMS-794833 (BMS794833)

Catalog No.: PC-42618Not For Human Use, Lab Use Only.

BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2 with IC50 of 1.7 nM/15 nM.

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5 mg	$78	In stock
10 mg	$118	In stock
25 mg	$188	In stock
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Biological Activity

BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2 with IC50 of 1.7 nM/15 nM.
BMS-794833 also inhibits Ron, Axl and Flt-3 with IC50<3 nM.
BMS-794833 shows selectivity over a panel of >200 RTKs, non-RTKs and serine/threonine kinases.
BMS-794833 inhibits the cell growth in GTL-16 gastric carcinomas with an IC50 of 39 nM.
BMS-794833 is active in multiple tumor models.

Physicochemical Properties

M.Wt	468.84
Formula	C23H15ClF2N4O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-Pyridinecarboxamide, N-[4-[(2-amino-3-chloro-4-pyridinyl)oxy]-3-fluorophenyl]-5-(4-fluorophenyl)-1,4-dihydro-4-oxo-

References

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BMS-794833 (BMS794833)

Biological Activity

Physicochemical Properties

References

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