Chemical Structure : BMS-794833
CAS No.: 1174046-72-0
Catalog No.: PC-42618Not For Human Use, Lab Use Only.
BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2 with IC50 of 1.7 nM/15 nM.
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BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2 with IC50 of 1.7 nM/15 nM.
BMS-794833 also inhibits Ron, Axl and Flt-3 with IC50<3 nM.
BMS-794833 shows selectivity over a panel of >200 RTKs, non-RTKs and serine/threonine kinases.
BMS-794833 inhibits the cell growth in GTL-16 gastric carcinomas with an IC50 of 39 nM.
BMS-794833 is active in multiple tumor models.
M.Wt | 468.84 | |
Formula | C23H15ClF2N4O3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
3-Pyridinecarboxamide, N-[4-[(2-amino-3-chloro-4-pyridinyl)oxy]-3-fluorophenyl]-5-(4-fluorophenyl)-1,4-dihydro-4-oxo- |
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