Catalog No.: PC-61119Not For Human Use, Lab Use Only.
BMS-814580 phosphate is a highly potent, subtype-selective melanin concentrating hormone receptor 1 (MCHR1) inhibitor with Ki of 17 nM, without inhibitory activity for MCHR2 at 10 uM.
BMS-814580 phosphate is a highly potent, subtype-selective melanin concentrating hormone receptor 1 (MCHR1) inhibitor with Ki of 17 nM, without inhibitory activity for MCHR2 at 10 uM.
BMS-814580 phosphate exhibits functional potency with Kb of 117 nM in FLIPR-based assay, with no activity for MCHR2 at 10 uM.
BMS-814580 phosphate dose-dependently reduces body weight in chronic diet-induced obese models with excellent safety profile.
