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BMS-820132

Chemical Structure : BMS-820132

CAS No.: 1001419-18-6

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BMS-820132 (BMS820132)

Catalog No.: PC-38112Not For Human Use, Lab Use Only.

BMS-820132 (BMS 820132) is potent, selective, partial glucokinase (GK) activator with AC50 of 29 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    BMS-820132 (BMS 820132) is potent, selective, partial glucokinase (GK) activator with AC50 of 29 nM.
    BMS-820132 displays promising in vivo efficacy and preclinical ADME and safety profiles for the treatment of type 2 diabetes.

    Physicochemical Properties

    M.Wt 572.559
    Formula C26H33N6O7P
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    diethyl ((3-(3-((5-(azetidine-1-carbonyl)pyrazin-2-yl)oxy)-5-isopropoxybenzamido)-1H-pyrazol-1-yl)methyl)phosphonate

    References

    1. Shi Y, et al. J Med Chem. 2022 Mar 10;65(5):4291-4317.

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