BMS-820132 | Glucokinase activator | Probechem Biochemicals

Chemical Structure : BMS-820132

BMS-820132 (BMS820132)

Catalog No.: PC-38112Not For Human Use, Lab Use Only.

BMS-820132 (BMS 820132) is potent, selective, partial glucokinase (GK) activator with AC50 of 29 nM.

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Biological Activity

BMS-820132 (BMS 820132) is potent, selective, partial glucokinase (GK) activator with AC50 of 29 nM.
BMS-820132 displays promising in vivo efficacy and preclinical ADME and safety profiles for the treatment of type 2 diabetes.

Physicochemical Properties

M.Wt	572.559
Formula	C26H33N6O7P
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	diethyl ((3-(3-((5-(azetidine-1-carbonyl)pyrazin-2-yl)oxy)-5-isopropoxybenzamido)-1H-pyrazol-1-yl)methyl)phosphonate

References

1. Shi Y, et al. J Med Chem. 2022 Mar 10;65(5):4291-4317.

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BMS-820132 (BMS820132)

Biological Activity

Physicochemical Properties

References

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