BMS-983970 |CAS:1584713-87-0 Probechem Biochemicals

Chemical Structure : BMS-983970

BMS-983970 (BMS983970)

Catalog No.: PC-43026Not For Human Use, Lab Use Only.

BMS-983970 (BMS983970) is a potent, orally active, pan-Notch inhibitor, demonstrates robust anti-tumor activity at tolerated doses in multiple tumor xenograft models..

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Biological Activity

BMS-983970 (BMS983970) is a potent, orally active, pan-Notch inhibitor, demonstrates robust anti-tumor activity at tolerated doses in multiple tumor xenograft models.

Physicochemical Properties

M.Wt	518.5032
Formula	C26H26F4N4O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO
Chemical Name/SMILES	Butanediamide, 3-(cyclopropylmethyl)-N1-[(3S)-9-fluoro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-2-(3,3,3-trifluoropropyl)-, (2R,3S)-

References

1. Ashvinikumar V. Gavai, et al. Abstract 1643: BMS-983970, an oral pan-Notch inhibitor for the treatment of cancer . Cancer Res October 1, 2014 74; 1643.

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BMS-983970 (BMS983970)

Biological Activity

Physicochemical Properties

References

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