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Chemical Structure : BMS-986001
Catalog No.: PC-61164Not For Human Use, Lab Use Only.
A thymidine analogue nucleoside reverse transcriptase inhibitor (NRTI) that inhibits HIV-2 isolates from treatment-naive individuals with EC50 of 30-81 nM.
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BMS-986001 (Censavudine, Festinavir, OBP-601) is a thymidine analogue nucleoside reverse transcriptase inhibitor (NRTI) that inhibits HIV-2 isolates from treatment-naive individuals with EC50 of 30-81 nM.
BMS-986001 (Censavudine, Festinavir, OBP-601) inhibits isolates of HIV-1 with EC50 of 450-890 nM, also exhibits full activity against HIV-2 variants whose genomes encoded the single amino acid changes K65R and Q151M in reverse transcriptase.
| M.Wt | 248.238 | |
| Formula | C12H12N2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Li Z, et al. Antimicrob Agents Chemother. 2013 Nov;57(11):5500-8.
2. Wang F, et al. Antimicrob Agents Chemother. 2013 Dec;57(12):6205-12.
3. Smith RA, et al. Antimicrob Agents Chemother. 2015 Dec;59(12):7437-46.
4. Gupta SK, et al. Lancet HIV. 2016 Jan;3(1):e13-22.
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