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Chemical Structure : BMS-986122
CAS No.: 313669-88-4
Catalog No.: PC-63080Not For Human Use, Lab Use Only.
BMS-986122 is a potent positive allosteric modulator of μ-opioid (MOR) receptor, significantly increases the inhibition of forskolin-stimulated adenylyl cyclase activity produced by an EC10 (30 pM) concentration of endomorphin-I in CHO-μ cells.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $198 | In stock | |
| 25 mg | $328 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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BMS-986122 is a potent positive allosteric modulator of μ-opioid (MOR) receptor, significantly increases the inhibition of forskolin-stimulated adenylyl cyclase activity produced by an EC10 (30 pM) concentration of endomorphin-I in CHO-μ cells.
| M.Wt | 448.774 | |
| Formula | C16H15BrClNO3S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-(3-Bromo-4-methoxyphenyl)-3-[(4-chlorophenyl)sulfonyl]-thiazolidine |
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1. Burford NT, et al. Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10830-5.
2. Livingston KE, et al. Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18369-74.
3. Livingston KE, et al. Mol Pharmacol. 2018 Feb;93(2):157-167.
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