BMS-986122 | MOR PAM | Probechem Biochemicals

Chemical Structure : BMS-986122

CAS No.: 313669-88-4

BMS-986122 (BMS986122)

Catalog No.: PC-22780Not For Human Use, Lab Use Only.

BMS-986122 is a positive allosteric modulator of μ-opioid receptor (MOR) with EC50 of 3.0 uM for increased β-arrestin recruitment by 20 nM endomorphin-I.

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Biological Activity

BMS-986122 is a positive allosteric modulator of μ-opioid receptor (MOR) with EC50 of 3.0 uM for increased β-arrestin recruitment by 20 nM endomorphin-I.

Physicochemical Properties

M.Wt	448.77
Formula	C16H15BrClNO3S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3-Bromo-4-methoxyphenyl)-3-[(4-chlorophenyl)sulfonyl]thiazolidine

References

1. Burford NT, et al. Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10830-5.

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BMS-986122 (BMS986122)

Biological Activity

Physicochemical Properties

References

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