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BMS-986163

Chemical Structure : BMS-986163

CAS No.: 1801151-09-6

BMS-986163 (BMS986163)

Catalog No.: PC-35167Not For Human Use, Lab Use Only.

BMS-986163 is a water-soluble phosphate prodrug of BMS-986169, which is a novel GluN2B negative allosteric modulator (Ki=4.0 nM)..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    BMS-986163 is a water-soluble phosphate prodrug of BMS-986169, which is a novel GluN2B negative allosteric modulator (Ki=4.0 nM).

    Physicochemical Properties

    M.Wt 462.458
    Formula C23H28FN2O5P
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-((3S,4S)-3-fluoro-1-((R)-1-(4-methylbenzyl)-2-oxopyrrolidin-3-yl)piperidin-4-yl)phenyl dihydrogen phosphate

    References

    1. Marcin LR, et al. ACS Med Chem Lett. 2018 Apr 13;9(5):472-477.

    2. Bristow LJ, et al. J Pharmacol Exp Ther. 2017 Dec;363(3):377-393.

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