BMS-986163 |CAS:1801151-09-6 Probechem Biochemicals

Chemical Structure : BMS-986163

Catalog No.: PC-35167Not For Human Use, Lab Use Only.

BMS-986163 is a water-soluble phosphate prodrug of BMS-986169, which is a novel GluN2B negative allosteric modulator (Ki=4.0 nM)..

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Biological Activity

BMS-986163 is a water-soluble phosphate prodrug of BMS-986169, which is a novel GluN2B negative allosteric modulator (Ki=4.0 nM).

M.Wt	462.458
Formula	C23H28FN2O5P
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-((3S,4S)-3-fluoro-1-((R)-1-(4-methylbenzyl)-2-oxopyrrolidin-3-yl)piperidin-4-yl)phenyl dihydrogen phosphate

1. Marcin LR, et al. ACS Med Chem Lett. 2018 Apr 13;9(5):472-477.

2. Bristow LJ, et al. J Pharmacol Exp Ther. 2017 Dec;363(3):377-393.