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BMS-986189

Chemical Structure : BMS-986189

CAS No.: 1629665-96-8

BMS-986189 (BMS986189)

Catalog No.: PC-22238Not For Human Use, Lab Use Only.

BMS-986189 is a macrocyclic thioether peptide antagonist of the PD-1/PD-L1 interaction.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

BMS-986189 is a macrocyclic thioether peptide antagonist of the PD-1/PD-L1 interaction.

Physicochemical Properties

M.Wt 1887.24
Formula C91H131N21O21S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Glycinamide, N-(2-mercaptoacetyl)-L-tyrosyl-N-methyl-L-alanyl-L-asparaginyl-L-prolyl-3-amino-L-alanyl-L-leucyl-(4R)-4-hydroxy-L-prolyl-L-tryptophyl-(2S)-2,4-diaminobutanoyl-1-(carboxymethyl)-L-tryptophyl-N-methyl-L-norleucyl-N-methyl-L-norleucyl-L-leucyl-L-cysteinyl-, cyclic (1→14)-thioether

References

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