BMS-986189 | PD-1/PD-L1 inhibitor | Probechem Biochemicals

Chemical Structure : BMS-986189

CAS No.: 1629665-96-8

Catalog No.: PC-22238Not For Human Use, Lab Use Only.

BMS-986189 is a macrocyclic thioether peptide antagonist of the PD-1/PD-L1 interaction with IC50 of 1.03 nM.

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2 mg	$128	In stock
5 mg	$248	In stock
10 mg	$398	In stock
25 mg	$598	In stock
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Biological Activity

BMS-986189 is a macrocyclic thioether peptide antagonist of the PD-1/PD-L1 interaction with IC50 of 1.03 nM.

M.Wt	1887.24
Formula	C91H131N21O21S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Glycinamide, N-(2-mercaptoacetyl)-L-tyrosyl-N-methyl-L-alanyl-L-asparaginyl-L-prolyl-3-amino-L-alanyl-L-leucyl-(4R)-4-hydroxy-L-prolyl-L-tryptophyl-(2S)-2,4-diaminobutanoyl-1-(carboxymethyl)-L-tryptophyl-N-methyl-L-norleucyl-N-methyl-L-norleucyl-L-leucyl-L-cysteinyl-, cyclic (1→14)-thioether

1. Yang J, et al. Front Oncol. 2022 Nov 17;12:992171.